Pertanto, i pazienti in terapia con azitromicina e antiacidi non devono assumere i due farmaci contemporaneamente. Tuttavia, la somministrazione di azitromicina ha determinato un aumento delle concentrazioni della zidovudina fosforilata, suo metabolita clinicamente attivo, nelle cellule periferiche mononucleate. Tuttavia, sono stati segnalati casi post-marketing di rabdomiolisi in pazienti in trattamento con azitromicina e statine. Efavirenz La somministrazione concomitante di una dose singola giornaliera di azitromicina mg e di efavirenz mg per 7 giorni non ha prodotto interazioni farmacocinetiche clinicamente significative. Fluconazolo La somministrazione concomitante di una dose singola di azitromicina mg non ha alterato la farmacocinetica di una dose singola di fluconazolo mg.

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