Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. Quinhentos e noventa e oito gatos receberamcetoconazol e itraconazol. Estes resultados sugeriram que o itraconazol foi mais efetivo e seguro que o cetoconazol. Abstract: Sporotrichosis is a mycosis caused by the dimorphic fungus Sporothrix schenckii. It affects human beings as well as a number of other animal species, with cats showing the highest incidence.

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Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. Quinhentos e noventa e oito gatos receberamcetoconazol e itraconazol.
Estes resultados sugeriram que o itraconazol foi mais efetivo e seguro que o cetoconazol. Abstract: Sporotrichosis is a mycosis caused by the dimorphic fungus Sporothrix schenckii. It affects human beings as well as a number of other animal species, with cats showing the highest incidence.
Cat-related disease transmission to humans has been rising in the last ten years in Rio de Janeiro. Feline sporotrichosis has various clinical presentations and its treatment is a challenge to veterinarians. Recommended therapeutic interventions so far have been based on observational studies of isolated cases or on case series and controlled prospective studies have not yet been carried out.
Itraconazole, as a first choice, and ketoconazole are the most commonly used medications. Iodides, terbinafine, local thermotherapy, amphothericin B and surgical resection of cutaneous lesions are other therapeutic options. The therapeutic schemes currently used in feline sporotrichosis treatment were assessed. The treatment was curative in two hundred and thirty-eight cats Adverse effects were reported in Our results suggest that itraconazole is more effective and safer than ketoconazole for the treatment of feline sporotrichosis.
A double-blind randomized controlled clinical trial was designed to test the efficacy and safety of different doses of ketoconazole and itraconazole for feline sporotrichosis treatment.
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